产品描述：

background: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to

transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing

isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the

kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter

protein PELI1.