货品编号: 博奥森.bs-14278R 品牌:博奥森 品名:乳腺癌细胞3抗体 规格:100ul
产品描述: background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some
form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding
domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a
member of the krueppel C2H2-type zinc-finger protein family, ZNF516 is a 1,163 amino acid nuclear protein that contains
ten C2H2-type zinc-fingers. The gene encoding ZNF516 maps to human chromosome 18, in a region that is frequently
found to be affected in 18q deletion syndrome, a multiple-anomaly mental retardation syndrome that is associated with
congenital aural atresia.
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