货品编号： 三箭.M100F1-02E 品牌：三箭 品名：FITC Anti-Mouse F4/80 Monoclonal Antibody BM8

产品描述：

F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family.

F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on majority of tissue

macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages

located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, bone marrow stromal cells. F4/80

has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that

F4/80 is required for induction of CD8 T cells-mediated peripheral tolerance.