产品描述： background: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in

prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the

nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein

is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in

spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution

gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe

spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been

found for this gene. [provided by RefSeq, Jun 2010].