货品编号： peprotech.af-200-04 品牌：peprotech 品名：Animal-Free Recombinant Human IL-4 规格：5ug

产品描述： Description:

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene

expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive

CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5,

IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of

immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated

with elevated IgE production and allergy. Recombinant Human IL-4 is a 15.1 kDa globular protein containing 130 amino

acid residues.