货品编号： 圣克鲁斯.sc-166613 品牌：圣克鲁斯 品名：Factor H Antibody (H-7) Alexa Fluor® 594 规格：200 µg/ml

产品描述：

Factor H抗体(H-7)是小鼠单克隆IgG1 (kappa轻链)，规格为200 µg/ml raised against amino acids 61-360 mapping within an internal region of Factor H of human origin 推荐用于 mouse, rat 和 human 来源的Factor H WB, IP, IF 和 ELISA检测 还可偶联琼脂糖， 用于 IP；偶联HRP，用于WB, IHC(P) 和 ELISA; 偶联FITC以及荧光素，用于IF, IHC(P) 和 FCM 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM,

以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如

LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统 The Factor H gene family is a multidomain, multifunctional protein family whose individual members are defined by conserved structural

elements, which display diverse yet often overlapping functions. These proteins share a common structural motif, the short consensus

repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species. The human complement

Factor H (FH, CFH, HUS, b-1H) gene encodes a 1213 amino acid serum glycoprotein which is arranged into 20 SCRs, each approximately 60

amino acids long, and an 18-residue leader sequence. Factor H controls the function of the alternative complement pathway and acts as a

cofactor with Factor I (C3b inactivator). In addition, Factor H has functional activity outside of the complement system, where it can bind to the

cellular integrin receptor (CD11b/CD18), interact with cell surface glycosaminoglycans and associate with the surface of certain pathogenic

microorganisms. Deficiencies in Factor H is a common characteristic of acute renal disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences