CB-13

简要描述：CB-13, also known as SAB-378, CRB-13, is a potent, orally active CB1/CB2 receptor agonist with limited brain penetration.

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Description:CB-13, also known as SAB-378, CRB-13, is a potent, orally active CB1/CB2 receptor agonist with limited brain penetration (EC50 values are 6.1 and 27.9 nM for CB1 and CB2 receptors respectively). It displays antihyperalgesic activity in a rat model of neuropathic pain with no CNS side effects.

Name: CB-13CAS#: 432047-72-8Chemical Formula: C26H24O2Exact Mass: 368.17763Molecular Weight: 386.47Elemental Analysis: C, 84.75; H, 6.57; O, 8.68

Synonym:CB-13; CB 13; CB13; CRA-13; CRA 13; CRA13; USAB-378; SAB 378; SAB378.

IUPAC/Chemical Name:1-Naphthalenyl(4-(pentyloxy)-1-naphthalenyl)methanone

InChi Key:RSUMDJRTAFBISX-UHFFFAOYSA-N

InChi Code:InChI=1S/C26H24O2/c1-2-3-8-18-28-25-17-16-24(21-13-6-7-14-22(21)25)26(27)23-15-9-11-19-10-4-5-12-20(19)23/h4-7,9-17H,2-3,8,18H2,1H3

SMILES Code:CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c4ccccc14

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