博奥森.bs-13021 RDNA聚合酶μ/DNA pol μ抗体 200ul Bioss


货品编号: 博奥森.bs-13021 品牌:博奥森 品名:RDNA聚合酶μ/DNA pol μ抗体 规格:200ul

产品描述:

DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase.

Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA

polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides

in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.

Function: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig)

light chain gene rearrangement in V(D)J recombination.

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