货品编号: 博奥森.bs-13021 品牌:博奥森 品名:RDNA聚合酶μ/DNA pol μ抗体 规格:200ul
产品描述:
DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase.
Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA
polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides
in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.
Function: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig)
light chain gene rearrangement in V(D)J recombination.
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