货品编号： thermo.T13343 品牌：thermo 品名：Transferrin From Human Serum, Alexa Fluor™ 594 Conjugate 规格：5mg

产品描述： Transferrin is a monomeric serum glycoprotein (~80,000 daltons) that binds to a specific receptor on the surface of vertebrate cells

and delivers up to two Fe3+ atoms via receptor-mediated endocytosis—our labeled LDL complexes are useful tools for studying this

phenomenon. Once iron-carrying transferrin proteins are inside endosomes, the acidic environment favors dissociation of iron from

the transferrin–receptor complex. Following the release of iron, the apotransferrin is recycled to the plasma membrane, where it is

released from its receptor to scavenge more iron. Fluorescent transferrin conjugates can therefore be used with fluorescent LDL to

distinguish the lysosomally directed and recycling endosomal pathways.

These experiments are typically performed by adding fluorescently labeled transferrin to cultured cells and analyzing them by microscopy.

We offer a biotinylated transferrin conjugate and more than 10 fluorescent versions.