人小肠上皮细胞
简要描述:Human small intestinal epithelial cells(人小肠上皮细胞)play a crucial role in food digestion,nutrient absorption.
金山科研平台微信:jinshanbio
product name:Human Small Intestine Epithelial Cells(人小肠上皮细胞);
cat no:ABC-TC3814;
Size/Quantity:1 vial;
Biosafety Level:1;
Shipping Info:Dry Ice;
Storage:Liquid Nitrogen;
Description:
Lining on the intestinal lumen surface, human small intestinal epithelial cells (IECs,人小肠上皮细胞) play a crucial role in food digestion, nutrient absorption and more importantly, constitutes a physical barrier that separates host from commensal microbiota. The crypts and villi border the surface area of intestinal epithelium and homes a variety of specialized epithelial lineages including absorptive enterocytes, enteroendocrine cells, goblet cells and Paneth cells. Unique to small intestine, Paneth cells lines in the base of crypts and secretes numerous antimicrobial peptides (AMPs) that strictly regulate antimicrobial resistance. Deregulated intestinal barrier function is often associated with increased risk of intestinal inflammation, systematic immune activation, development of inflammatory bowel disease (IBD) and increased sensitivity to chronic viral infections.;
Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi;
Application:For research use only.
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