货品编号： Thermo.14-0808-82 品牌：Thermo 品名：ANTI-MOUSE CD8A (4SM15) PURIFIED 规格：100ug

产品描述： Description:

The 4SM15 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor

expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of

thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a

subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I

and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.