货品编号： 博奥森.bs-0737R 品牌：博奥森 品名：缺氧诱导因子1α /低氧诱导因子-1抗体 规格： 20ul

产品描述： background: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen

tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer

composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon

receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural

antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two

alternative transcripts encoding different isoforms have been identified.