货品编号: apexbio.A3516
品牌: apexbio
品名: JC-1线粒体膜电位探针
规格: 1mg
产品描述:
JC-1 is a dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential.
JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms
red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra.
The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by
mitochondrial size, shape, or density. JC-1 is particularly useful for apoptosis studies. In apoptotic cells, the dye
stays in the cytoplasm and fluoresces green, while in healthy cells, the dye aggregates in the mitochondria and fluoresces red.
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