货品编号： bioss.bs-1165R

品牌： bioss

品名： Rabbit Anti-Beta catenin antibody (bs-1165R) 试用装

规格： 10ul

产品描述：

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs).

AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and

adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible

for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is

complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous

polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR),

medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have

been found for this gene.[provided by RefSeq, Oct 2009].