货品编号： 博奥森.bs-8098R

品牌： 博奥森

品名： 卷曲螺旋结构域蛋白34抗体

规格： 100ul

产品描述：

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions

such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34

(coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein

that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of

chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal

pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.

DISEASE:

Note=A chromosomal aberration involving CCDC34 is found in a patient with hamartoma of the retinal pigment epithelium

and retina. Translocation t(11;18) (p13;p11.2).