货品编号: bioss.bs-15349R
品牌: bioss
品名: Rabbit Anti-C9orf95/NRK antibody
规格: 100ul
产品描述:
Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor involved in fundamental processes in cell metabolism.
NRK1 (Nicotinamide riboside kinase 1), also known as Ribosylnicotinamide kinase 1, is a 199 amino acid enzyme is involved
in the synthesis of NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor. Nicotinamide
riboside has been idenitifed as a nutrient in milk, suggesting that it is a useful compound for elevating the NAD+ levels in
humans. NRK1 also phosphorylates the anti-cancer drugs tiazofurin and 3-deazaguanosine, which converts them into toxic
NAD+ analogs and leads to the inhibition of guanine nucleotide biosynthesis. There are two isoforms of NRK1 that are produced
as a result of alternative splicing events.
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