品牌： bioss

品名： Rabbit Anti-Connexin 43 antibody

规格： 50ul

产品描述：

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed

of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The

encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized

contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5.

Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. [provided by RefSeq].

Function:

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of

transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play

a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator

of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles

to cholinergic neural stimuli and causing them to contract.