货品编号： 博奥森.bs-1310R

品牌： 博奥森

品名： Integrin Alpha V + Beta 3 (CD51+CD61)

规格： 100ul

产品描述：

Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. They are known to participate in

cell adhesion as well as cell-surface mediated signalling. Integrins are heterodimeric integral membrane proteins composed

of an alpha chain and a beta chain.

CD51 encodes integrin alpha chain V. The I-domain containing integrin alpha V undergoes post-translational cleavage to

yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. The

CD61 protein product is the integrin beta chain beta 3. Integrin beta 3 is found along with the alpha IIb chain in platelets.

Integrin alpha V/beta 3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase 2, osteopontin, osteomodulin,

prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha V/beta 3 recognizes the sequence R-G-D in

a wide array of ligands. The alpha V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix

metalloproteinase 2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the

sequence R-G-D in a wide array of ligands.