品牌： Invitrogen

品名： Ly-6G Monoclonal Antibody (1A8-Ly6g), APC, eBioscience™

规格： 100ug/支

产品描述：

Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25-kDa

GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and

migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The

ligand for Ly-6G is currently unknown.

Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been

used to deplete neutrophils and reported to have antagonist activity.

Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can

be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in

a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is

recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.

Filtration: 0.2 µm post-manufacturing filtered.