品牌： sigma

品名： 单克隆抗肌球蛋白（骨骼，快速）小鼠抗

规格： 0.2ml

产品描述：

Monoclonal Anti-Skeletal Myosin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma

cells and splenocytes from an immunized mouse. Myosin is a 480,000 dalton protein known to interact with actin in muscle and in

non-muscle cells. It contains two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons).

Myosin molecules consist of two major regions: tails (rods) and heads;[5] they aggregate into filaments through the tail region and

interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal,

cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function

of the muscle. These are designated at type I (slow twitch) and type II (fast-twitch). Type II fibers can be further subdivided in types IIA,

IIB, and IIC.[5]

定位于肌球蛋白重链上的表位。可对骨骼肌中发现的快速（II型）和新生儿肌动蛋白分子进行染色，但不会对培养细胞中的心肌、平滑

肌或非肌肉肌球蛋白染色。能与人类横纹肌肉瘤发生反应。