货品编号： bioss.bsm-41411m品牌： bioss品名： Anti- SARS- CoV-2 N protein monoclons1 anti body规格： 1mg产品描述：

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry.

Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected

primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus

RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most

abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical

nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication

and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity,

the N protein of coronavirus is chosen as a diagnostic tool.