货品编号： bioss.bs-20594R 品牌：bioss 品名：Rabbit Anti-TLR4 antibody 规格：50ul

产品描述： The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like

receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation

in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded

or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was

made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least

one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a

YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their

source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP

database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the

inflammatory condition associated with nonseptic thermal injury.

Function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via

MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also

involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved

histidines and are, therefore, species-specific.