货品编号: Bioss.bs-23258R 品牌:Bioss 品名:Anti-Osteopontin骨桥蛋白/分泌型磷蛋白1抗体
规格:100ul
研究领域 神经生物学信号转导生长因子和激素 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Rat, 产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 34kDa 细胞定位 分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from rat osteopontin:201-314/314 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed
产品介绍
Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine. Osteopontin
is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the
mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including
lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma.
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