货品编号: Bioss.bs-0013R品牌: Bioss品名: Anti-Cytochrome C细胞色素C抗体规格: 100ul 研究领域:肿瘤 心血管 细胞生物 神经生物学 信号转导 细胞凋亡 脂蛋白 新陈代谢 线粒体
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig,
产品应用:WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量:12.8/26kDa
细胞定位:细胞浆 细胞膜 线粒体
性 状:Liquid
浓 度:1mg/ml
免 疫 原:KLH conjugated synthetic peptide derived from human Cytochrome C:51-105/105
亚 型:IgG
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed:PubMed
产品介绍:Cytochrome C is an electron transporting protein that resides within the intermembrane space
of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production
of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has
been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is
rapidly released from the mitochondria into the cytosol, an event which may be required for the completion
of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family
molecule that is a key effector of apoptosis.
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