货品编号： Bioss.bs-0157R

品牌： Bioss

品名： Anti-Tau微管相关蛋白抗体

规格： 100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Rabbit,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量52/79kDa

细胞定位细胞浆 细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Tau protein:681-758/758

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Tau proteins are important Promotes microtubule assembly and stability, and might be involved

in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while

the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein

between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the

cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer

isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons,

in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed

in the peripheral nervous system while the others are expressed in the central nervous system.