货品编号： Bioss.bs-0255R

品牌： Bioss

品名： Anti-Estrogen receptor beta雌激素受体β抗体

规格： 100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量58kDa

细胞定位细胞核

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ER-Beta:50-100/530

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a member of the family of estrogenreceptors and superfamily of nuclear receptor transcriptionfactors.

The gene product contains an N-terminal DNA binding domainand C-terminal ligand binding domain and is localized to thenucleus,

cytoplasm, and mitochondria. Upon binding to17beta-estradiol or related ligands, the encoded protein formshomo- or hetero-dimers

that interact with specific DNA sequences toactivate transcription. Some isoforms dominantly inhibit theactivity of other estrogen

receptor family members. Severalalternatively spliced transcript variants of this gene have beendescribed, but the full-length nature

of some of these variants hasnot been fully characterized. [provided by RefSeq, Jul 2008].