货品编号： Bioss.bs-3705R 品 牌：Bioss 品 名：Anti-phospho-P53 (Ser33)磷酸化肿瘤抑制基因P53抗体

规 格：100ul

产品类型 磷酸化抗体研究领域肿瘤免疫学信号转导转录调节因子抗体来源 Rabbit克隆类型 Polyclonal交叉反应 Human,Mouse,Horse,产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1μg /TestIF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.分子量 43kDa细胞定位 细胞核细胞浆性状 Liquid浓度 1mg/ml免疫原 KLH conjugated Synthesised phosphopeptide derived from human P53 around the phosphorylation site of Ser33:VL(p-S)PL亚型 IgG纯化方法 affinity purified by Protein A储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMed PubMed产品介绍This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The

encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis,

senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including

hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple

transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons

(PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].