Bioss.bs-0830R Anti-44108 胚胎干细胞关键蛋白抗体 100ulBioss


货品编号Bioss.bs-0830R

品牌Bioss

品名Anti-44108胚胎干细胞关键蛋白抗体

规格100ul

研究领域细胞生物 染色质和核信号 信号转导 干细胞 细胞周期蛋白 转录调节因子 细胞类型标志物 表观遗传学

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 (石蜡切片需做抗原修复)

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量39kDa

细胞定位细胞核

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Octamer4:201-300/360

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a

hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by

its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to

somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent

stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in

mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem

cells in an uncommitted state.

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