货品编号Bioss.bs-10196R-100ul

品牌Bioss

品名Anti-alpha smooth muscle Actin肌动蛋白α/α-SMA/α Actin抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Rabbit,

产品应用WB=1:5000-20000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量42kDa

细胞定位细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human alpha-SMA:165-260/377

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments

can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus

of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several

isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into

three classes. alpha-Actin expression is limited to various types of muscle, whereas beta- and gamma-Actin are

the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization

of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin

filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.