货品编号Bioss.bs-1047R

品牌Bioss

品名Anti-MyD88髓样分化蛋白抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量34kDa

细胞定位细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from mouse MyD88:201-296/296

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.

This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.

These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an

N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have

an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.