货品编号Bioss.bs-12911R

品牌Bioss

品名Anti-Phospho-c-Fos (Ser374)磷酸化c-fos抗体

规格100ul

产品类型磷酸化抗体

研究领域肿瘤 细胞生物 免疫学 神经生物学 信号转导 转录调节因子 肿瘤细胞生物标志物

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量41kDa

细胞定位细胞核

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated Synthesised phosphopeptide derived from human c-Fos around the phosphorylation site of Ser374:LS(p-S)PT

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper

proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.

As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

In some cases, expression of the FOS gene has also been associated with apoptotic cell death.