货品编号： Bioss.bsm-33283M 品 牌： Bioss 品 名：Anti-BaxBax单克隆抗体 规 格： 100ul 研究领域 肿瘤细胞生物细胞凋亡细胞外基质 抗体来源 Mouse 克隆类型 Monoclonal 克隆号 3C1 交叉反应 Human,Mouse,Rat,Monkey,Insect, Yeast 产品应用 WB=1:1000-1500ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100IF=1:200-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 21kDa 细胞定位 细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human Bax: 亚型 IgG1 纯化方法 affinity purified by Protein G 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

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产品介绍 The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as

anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2,

and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-

dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of

this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively

spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].