货品编号Bioss.bs-17502R

品牌Bioss

品名Anti-phospho-NFKB p65 (Ser281)磷酸化细胞核因子抗体

规格100ul

研究领域肿瘤 细胞生物 染色质和核信号 信号转导 激酶和磷酸酶 表观遗传学

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量61kDa

细胞定位细胞核 细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthesised phosphopeptide derived from human NFKB p65 around the phosphorylation site of Ser281:EL(p-S)EP

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in

an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates

transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The

most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants

encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].