货品编号Bioss.bs-20003R

品牌Bioss

品名Anti-RUNX2核心结合因子α1/成骨特异性转录因子/Cbfα1抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量57(hu)/67(mo,ratkDa

细胞定位细胞核

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human RUNX2:201-300/521

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt

DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and

acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can

bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this

gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript

variants that encode different protein isoforms result from the use of alternate promoters as well as alternate

splicing. [provided by RefSeq, Jul 2008].