货品编号： bioss.bs-7158R 品 牌：bioss 品 名：I型胶原蛋白/胶原蛋白1/1型胶原蛋白/I型胶原a1抗体 规 格： 100ul/支 产品描述： 研究领域 肿瘤细胞生物免疫学 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep, 产品应用 WB=1:500-2000ELISA=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 130kDa 细胞定位 细胞外基质分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human Collagen alpha-1(I) chain:201-300/1464 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that

is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in

the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal

translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located,

are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression

of the growth factor.