货品编号: 博奥森.bs-5420R 品 牌:博奥森 品 名:磷酸化微管相关蛋白抗体 规 格: 100ul 研究领域 免疫学神经生物学转录调节因子 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit, 产品应用 WB=1:500-2000ELISA=1:500-1000Flow-Cyt=1μg/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 52/79kDa 细胞定位 细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated Synthesised phosphopeptide derived from human MAPT isoform 2 around the phosphorylation site of Thr205:SR(p-T)PS 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance
of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components,
suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in
the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms
may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association
with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are
expressed in the central nervous system.
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