货品编号： bioss.bs-10344R-10ul 品 牌：bioss 品 名：Rabbit Anti-AMPK alpha-1 antibody (bs-10344R) 规 格： 试用装 产品描述： 研究领域 细胞生物神经生物学激酶和磷酸酶通道蛋白细胞膜受体Alzheimer's 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Cow,Rabbit,Sheep, 产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500Flow-Cyt=0.2ug/Test（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 64kDa 细胞定位 细胞核细胞浆 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human AMPK alpha-1:351-450/559 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the

5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase

activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number

of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-

consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.