货品编号： Biossbs-2188R-50ul 品 牌：Bioss 品 名：Anti-GAPDH(Loading Control)(50ul) 规 格： 50ul 产品描述： 产品类型 内参抗体 研究领域 免疫学 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat, (predicted: Rabbit,) 产品应用 WB=1:2000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 37kDa 细胞定位 细胞核细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 GAPDH protein of rabbit: 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis.

As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also

involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase

activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the

role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related

neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed

in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase

GAPDH expression in certain cell types. GAPDH molecule is composed of four 38kDa subunits.