货品编号：博奥森.bs-2760R

品牌：博奥森

品名：皮层肌动蛋白抗体

规格：50ul

研究领域肿瘤 细胞生物 免疫学 信号转导 细胞粘附分子

抗体来源Rabbit

克隆类型Polyclonal

交叉反应(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )

产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量61kDa

细胞定位细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Cortactin:481-550/550

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein

is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the

interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures

of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The

aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different

isoforms have been identified for this gene. [provided by RefSeq].