货品编号:博奥森.bs-0027R
品牌:博奥森
品名:褪黑素受体1A/松果体素受体1A抗体
规格:50ul
研究领域肿瘤 细胞生物 神经生物学 信号转导 细胞膜受体 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Sheep, Guinea Pig, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量39kDa
细胞定位细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from the midlle of human MTR-1A:201-280/350 <Cytoplasmic>
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal
gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian
circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is
readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears
to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects
of melatonin.
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