货品编号：博奥森.bs-0755R-50ul

品牌：博奥森

品名：3-磷酸甘油醛脱氢酶

规格：50ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Rat, (predicted: Mouse, )

产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量37kDa

细胞定位细胞核 细胞浆 细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from the middle of human GAPDH:231-335/335

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis.

It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of

glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD).

Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion,

phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated

in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s

and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making

it ideal for use as a loading control marker in immunoblots.