货品编号：博奥森.bs-0117R
品牌：博奥森
品名：转移生长因子β受体2抗体
规格：100ul
研究领域肿瘤细胞生物神经生物学信号转导生长因子和激素激酶和磷酸酶细胞膜受体细胞分化 抗体来源Rabbit 克隆类型Polyclonal 交叉反应Human,Mouse,Rat,Cow,(predicted:Chicken,Pig,Horse,Rabbit,Sheep,) 产品应用WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）notyettestedinotherapplications.optimaldilutions/concentrationsshouldbedeterminedbytheenduser. 分子量62kDa 细胞定位细胞膜 性状Liquid 浓度1mg/ml 免疫原KLHconjugatedsyntheticpeptidederivedfromhumanTGFbetaReceptorII:241-330/567<Cytoplasmic> 亚型IgG 纯化方法affinitypurifiedbyProteinA 储存液0.01MTBS(pH7.4)with1%BSA,0.03%Proclin300and50%Glycerol. 保存条件Shippedat4℃.Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles. PubMedPubMed 产品介绍ThisgeneencodesamemberoftheSer/ThrproteinkinasefamilyandtheTGFBreceptorsubfamily.Theencodedproteinisatransmembrane
proteinthathasaproteinkinasedomain,formsaheterodimericcomplexwithanotherreceptorprotein,andbindsTGFbeta.Thisreceptorgand
complexphosphorylatesproteins,whichthenenterthenucleusand regulatethetranscriptionofasubsetofgenesrelatedtocellproliferation.
MutationsinthisgenehavebeenassociatedwithMarfanSyndrome,LoeysDeitzAorticAneurysmSyndrome,andthedevelopmentofvarious
typesoftumors.Alternativelysplicedtranscriptvariantsencodingdifferentisoformshavebeencharacterized.
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