货品编号: Biolegend.149309
品牌: Biolegend
品名: FITC anti-mouse CD182 (CXCR2) Antibody
规格: 25 µg
Amyloid beta (Aβ or Amyloid beta) denotes peptides of 36-43 amino acids in length that are crucially involved in
Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The
peptides result from the amyloid precursor protein (APP), which is cut by certain enzymes to yield Aβ. Aβ molecules
can aggregate to form oligomers (known as "seeds") which are believed to be able to induce other Aβ molecules to
also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The seeds or the resulting
amyloid plaques are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms
such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold.
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