货品编号： Bioss.bs-1482R

品牌： Bioss

品名： Rabbit Anti-CD177 antibody

规格： 200ul

产品编号bs-1482R英文名称CD177中文名称嗜中性粒细胞抗原CD177抗体别名NB1 GP; PRV-1; HNA-2a; NB1 glycoprotein; Neutrophil Glycoprotein NB1; RGD1562941; CD177 antigen; Polycythemia rubra vera protein 1; PRV-1; NB1 glycoprotein; NB1 GP; Human neutrophil alloantigen 2a; HNA-2a; CD177; NB1; CD177_MOUSE.Specific References(4)|bs-1482R has been referenced in 4 publications.[IF=3.97]Han, Feifei, et al. "Oral administration of yeast β-glucan ameliorates inflammation and intestinal barrier in dextran sodium sulfate-induced acute colitis." Journal of Functional Foods 35 (2017): 115-126.IHC-P;Mouse.PubMed:10.1016/j.jff.2017.05.036[IF=3.73]Scott, Jason A., et al. "The Multifunctional Ca2+/Calmodulin-Dependent Kinase IIdelta (CaMKIIdelta) Regulates Arteriogenesis in a Mouse Model of Flow-Mediated Remodeling." PloS one 8.8 (2013): e71550.IHC-P;Mouse.PubMed:23951185[IF=3.7]Yang, Jian, et al. "Ultrastructure damage of oviduct telocytes in rat model of acute salpingitis." Journal of Cellular and Molecular Medicine (2015).IHC-P;Rat.PubMed:25753567[IF=3.166]Ning YL et al. Caffeine attenuates brain injury but increases mortality induced by high-intensity blast wave exposure. (2019) Toxicology Letters;Feb;301:90-97. IHC;Mouse.PubMed:30423366研究领域免疫学细胞表面分子糖蛋白抗体来源Rabbit克隆类型Polyclonal交叉反应Mouse,Rat,产品应用WB=1:500-2000IHC-P=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.分子量90kDa细胞定位细胞膜性状Liquid浓度1mg/ml免疫原KLH conjugated synthetic peptide derived from rat CD177:521-650/818亚型IgG纯化方法affinity purified by Protein A储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed产品介绍This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]Subcellular Location:Cell membrane; Lipid-anchor, GPI-anchor.Tissue Specificity:Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).Similarity:Contains 2 UPAR/Ly6 domains.SWISS:D3ZCH9Gene ID:499099Database links:

Entrez Gene: 57126Human

Entrez Gene: 499099Rat

Omim: 162860Human

SwissProt: Q8N6Q3Human

Unigene: 232165Human

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.产品图片Sample:Lane 1: Spleen (Mouse) Lysate at 40 ugLane 2: Raw264.7 (Mouse) Cell Lysate at 30 ugLane 3: Lymph node (Rat) Lysate at 40 ugPrimary: Anti-CD177 (bs-1482R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 90-120 kDObserved band size: 130 kD