Bioss.bs-7949R Rabbit Anti-AOC1 antibody 200ulBioss


货品编号: Bioss.bs-7949R

品牌: Bioss

品名: Rabbit Anti-AOC1 antibody

规格: 200ul

产品编号bs-7949R
英文名称AOC1
中文名称阿米洛利结合蛋白1抗体
别名ABP; Abp1; ABP1_HUMAN; Amiloride binding protein 1 (amine oxidase (copper containing)); Amiloride binding protein 1; Amiloride binding protein; Amiloride sensitive amine oxidase; Amiloride-binding protein; Amiloride-sensitive amine oxidase [copper-containing]; DAO; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase.
Specific References(1)|bs-7949R has been referenced in 1 publications.[IF=10.754]Apolloni S et al. Histaminergic transmission slows progression of amyotrophic lateral sclerosis. J Cachexia Sarcopenia Muscle. 2019 Apr 24.WB&ICF;Mouse.PubMed:31020811
研究领域细胞生物免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, (predicted: Human,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
产品应用ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
分子量83kDa
细胞定位细胞外基质分泌型蛋白
性状Liquid
浓度1mg/ml
免疫原KLH conjugated synthetic peptide derived from human AOC1:601-689/751
亚型IgG
纯化方法affinity purified by Protein A
储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.Function:Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.Subunit:Homodimer; disulfide-linked.Subcellular Location:Secreted, extracellular space.Tissue Specificity:Placenta and kidney.Post-translational modifications:Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.Similarity:Belongs to the copper/topaquinone oxidase family.SWISS:P19801Gene ID:26Database links:

Entrez Gene: 26Human

Omim: 104610Human

SwissProt: P19801Human

Unigene: 647097Human

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAO1) Polyclonal Antibody, Unconjugated (bs-7949R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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