Bioss.bs-12081R Rabbit Anti-GABARE antibody 200ulBioss


货品编号: Bioss.bs-12081R

品牌: Bioss

品名: Rabbit Anti-GABARE antibody

规格: 200ul

产品编号bs-12081R
英文名称GABARE
中文名称G氨基丁酸受体ε/GABAA Rε抗体
别名GABA Receptor Epsilon; GABA(A) receptor epsilon; GABA(A) receptor subunit epsilon; Gabre; Gamma aminobutyric acid (GABA) A receptor epsilon; Gamma aminobutyric acid receptor subunit epsilon; Gamma-aminobutyric acid receptor subunit epsilon; GBRE_HUMAN.
研究领域神经生物学通道蛋白细胞膜受体G蛋白偶联受体G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应(predicted: Human,Mouse,Rat,Dog,Horse,)
产品应用ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
分子量56kDa
细胞定位细胞膜
性状Liquid
浓度1mg/ml
免疫原KLH conjugated synthetic peptide derived from human GABARE/GABA Receptor Epsilon:54-150/506<Extracellular>
亚型IgG
纯化方法affinity purified by Protein A
储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008]Function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.Subunit:Generally pentameric. Associates with alpha and beta subunits.Subcellular Location:Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.Tissue Specificity:Expressed in many tissues. Highest levels of expression in adult heart and placenta.Similarity:Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.GABRE sub-subfamily.SWISS:P78334Gene ID:2564Database links:

Entrez Gene: 2564Human

Entrez Gene: 65191Rat

Omim: 300093Human

SwissProt: P78334Human

SwissProt: Q9ES14Rat

Unigene: 22785Human

Unigene: 54455Rat

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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