博士德.A00276-1 Anti-EpCAM Antibody 50ul博士德


货品编号: 博士德.A00276-1

品牌: 博士德

品名: Anti-EpCAM Antibody

规格: 50ul

货号A00276-1
产品名称Anti-EpCAM Antibody
基因名Epcam
抗体来源Rabbit
克隆Polyclonal
抗体亚型Rabbit IgG
免疫原E.coli-derived mouse EpCAM recombinant protein (Position: E147-N189).
内容500 ug/ml antibody with PBS ,0.02% NaN3 , 1 mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500 ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
研究类别1. Litvinov, Sergey; et al. (1994). "Ep-CAM: a human epithelial antigen is a homophilic cell–cell adhesion molecule". The Journal of Cell Biology 125 (2): 437–46.2. Maetzel, Dorothea; et al. (2009). "Nuclear signalling by tumour-associated antigen EpCAM". Nature Cell Biology 11 (2): 162–71.
Uniprot IDEpcam:Q99JW5
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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