货品编号： Sigma.SML0223-10MG

品牌： Sigma

品名： Zoledronic acid

规格： 10MG/支

Biochem/physiol Actions Zoledronic acid (zoledronate) is a bisphosphonate bone resorption inhibitor, an inhibitor of farnesyl diphosphate (FPP) synthase which results in downstream inhibition of osteoclast activity and reduced bone resorption and turnover. It has been used to treat postmenopausal osteoporosis, Paget′s disease, hypercalcemia, and along with cancer chemotherapy to treat bone damage caused by cancer that has spread to the bones.

Features and Benefits This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

性质

Related Categories Bioactive Small Molecule Alphabetical Index, Kinase Regulators, Lipids in Cell Signaling, Phospholipid Metabolism, Z, 生物活性小分子, 甲羟戊酸途径中的抑制剂和激活剂, 癌症中的甲羟戊酸途径, 癌症代谢, 癌症研究, 细胞信号转导和神经科学, 细胞生物学

assay ≥98% (HPLC) formpowder storage condition desiccated protect from light color white to beige solubility H2O: ≥2 mg/mL storage temp. 2-8°C

安全信息