货品编号： Invitrogen.11-0080-81 品牌： Invitrogen 品名： Anti-Rat CD8b FITC 规格： 50ug

产品描述

Description: The eBio341 monoclonal antibody reacts with rat CD8beta. CD8beta is a member of the immunoglobulin superfamily which

heterodimerizes with CD8alpha to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC

class I-restricted peripheral T cells, and on some macrophages. CD8beta expression is absent in athymic mice, which are populated by

T-cells expressing CD8alpha homodimers. This has led to the idea that CD8beta expression is dependent on the development of T cells

in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates

in T-cell receptor signal transduction through association with the kinase Lck.

Applications Reported: This eBio341 (341) antibody has been reported for use in flow cytometric analysis.

Applications Tested: This eBio341 (341) antibody has been tested by flow cytometric analysis of rat splenocytes and thymocytes. This can

be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume

of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be

carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.