货品编号： Peprotech.214-14-50 品牌：Peprotech 品名：Recombinant Murine IL-4 规格：50µg

Product Details Catalog Number: 214-14 Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and

gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T

cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and

IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching

to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.

Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.